Hello,
We are running Windows 7 64-bit machines with Internet Explorer 10. We've noticed sporadic issues in the last few months where Internet Explorer randomly becomes unresponsive when launching. The only way we have of resolving is to either clear the cache on the machine, reboot, or clear the Local directory in the user's profile from their machine, in addition to the Local folder on the share we use for Persona Management. This also clears up the issue where the iexplore.exe process will not end, despite the application being closed.
We haven't seen this happen on machines where Persona Management is not set up. It seems like Persona Management is causing some corruption with the local web cache, but we haven't been able to pinpoint exactly how. Any suggestions?