I have a couple pools that are set up the same way with persistent disks. I have some users that, when trying to login, get "The User Profile Service failed the logon. User profile cannot be loaded." as an error, not allowing them to login with domain creds. When I log in as a local admin, I see that I don't have permissions to the persistent disk, which is where the user profiles are pointed.
Is this a profile problem or some kind of configuration problem?
The GPOs fore removable media/storage were not configured. I did set them to disabled so that they wouldn't block anything, but still no luck.